Immune development in late preterm neonates

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Immune development in late preterm neonates

Several recent studies have underlined that late preterm infants have a significantly increased risk of infection and sepsis, [1-3] mainly related to problems of adaptation from intrato extra-uterine life of the immune defense mechanisms. Indeed, both the innate (natural, non specific) and the adaptive (acquired, specific) immune systems are incompletely developed at birth, the more preterm the...

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Immune status in very preterm neonates.

OBJECTIVES Preterm neonates are at increased risk of sepsis compared with those born at term. We investigated immune status at birth and early neonatal life in very preterm neonates and its association with short-term outcomes. METHODS Prospective observational study conducted at a university hospital recruiting 113 preterm neonates (23-32 weeks) and 78 controls. Monocyte major histocompatibi...

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Periventricular Hemorrhage in Term and Late Preterm Neonates: Risk Factors and Outcomes

Background: Periventricular hemorrhage (PVH) is common in early preterm neonates but much less common in term and late preterm neonates. The aim of this study was to identify the risk factors and outcomes of PVH in term and late preterm neonates in a tertiary care center in Upper Egypt. Methods: A total of 33 term and late preterm (≥ 34 weeks...

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Prediction of Respiratory Morbidities in Late Preterm Neonates Using Cord Blood Arterial Lactate and Base Excess

Background: Late preterm neonates may have the external appearance and behavior similar to their counterparts.However, they are susceptible to various neonatal morbidities , due to their physiological and metabolical immaturity.To assess the correlation between cord blood arterial lactate levels and base excess with the development ofrespiratory distress in late preterm neonat...

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Neutrophil functions in late preterm neonates with respiratory distress syndrome

INTRODUCTION The innate immune system is the first line of host defense against invading microorganisms. In order to achieve this, neutrophils must be able both to circulate freely in the blood and to migrate as adherent cells into the extravascular tissues to phagocytose and kill invading microorganisms effectively. Most studies of neutrophil function have been conducted under conditions of am...

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ژورنال

عنوان ژورنال: Italian Journal of Pediatrics

سال: 2014

ISSN: 1824-7288

DOI: 10.1186/1824-7288-40-s2-a40